As the first rounds of the Covid-19 vaccines become available, a growing debate has emerged as to who should get it first. CDC guidance prioritizes essential workers and those in long-term care, but a growing chorus of voices say authorities should instead focus on the elderly. It’s a profound debate with broad ethical implications that dig into the question of preserving first-responders and society’s first line of defense versus rising morbidity and mortality rates among at-risk populations. Host and moderator John Donvan examines it all in a wide ranging interview with Dr. Larry Brilliant, physician, epidemiologist, and CEO of the Pandefense Advisory, who was also a part of the World Health Organization team that eradicated smallpox.